For the POC studies (internal and independent), we have worked with three 'drug' types and with a primary focus on pulsatile release.
We have, however, been involved in work targeting sustained delivery subsequent to a delay of release. Specifically, the pulsatile delivery programs have entailed work with:
The sustained release studies have mostly been with the high potency anthelmintic Ivermectin. However, we have been collaborating in development of sustained release 'hormone devices' for application in sheep and pigs using the combined effects from 'drug formulating' and the Controlled Release 'devices' to affect alterations to the hormones pharmaco kinetic profiles.
Biodegradable Vaccine Implant Trials
Trial A: 21 day Controlled Release Vaccine Formulation in Sheep
Trial B: 25 and 100 day Controlled Release Vaccine study in CattleBiodegradable Anthelmintic Delivery Trial
Trial C: 42 and 150 day Controlled Release Anthelmintic in Sheep
Repeatability and Reproducibility